| Date | Location | Result | |
| 2/22/22 | New Paltz, NY (Hawk Center) | New Paltz 84, Cortland 81 | Box score |
| 2/19/22 | Cortland, NY (Corey Gym) | Cortland 74, Geneseo 66 | Box score |
| 2/18/22 | Cortland, NY (Corey Gym) | Cortland 103, Buffalo St. 90 | Box score |
| 2/15/22 | Buffalo, NY (Buffalo St. Sports Arena) | Cortland 73, Buffalo St. 66 | Box score |
| 2/12/22 | New Paltz, NY (Hawk Center) | Cortland 82, New Paltz 71 | Box score |
| 2/11/22 | Oneonta, NY (Dewar Arena) | Oneonta 86, Cortland 72 | Box score |
| 2/5/22 | Cortland, NY (Corey Gym) | Cortland 83, Potsdam 56 | Box score |
| 2/4/22 | Cortland, NY (Corey Gym) | Cortland 95, Plattsburgh 61 | Box score |
| 2/1/22 | Cortland, NY (Corey Gym) | Cortland 89, Fredonia 66 | Box score |
| 1/29/22 | Cortland, NY (Corey Gym) | Oneonta 76, Cortland 70 | Box score |
| 1/28/22 | Cortland, NY (Corey Gym) | New Paltz 73, Cortland 71 | Box score |
| 1/22/22 | Cortland, NY (Corey Gym) | Oswego 72, Cortland 64 | Box score |
| 1/18/22 | Brockport, NY (Vlogianitis Gym) | Brockport 59, Cortland 58 | Box score |
| 1/14/22 | Potsdam, NY (Jerry Welsh Gym) | Cortland 81, Potsdam 72 | Box score |
| 1/13/22 | Plattsburgh, NY (Memorial Hall) | Cortland 82, Plattsburgh 52 | Box score |
| 1/6/22 | Scranton, PA (John Long Center) | Scranton 91, Cortland 58 | Box score |
| 1/4/22 | Cortland, NY (Corey Gym) | Cortland 90, Ithaca 58 | Box score |
| 12/18/21 | Cobleskill, NY (Iorio Gym) | Cortland 94, Cobleskill 75 | Box score |
| 12/8/21 | Geneseo, NY (Schrader Gym) | Geneseo 76, Cortland 70 | Box score |
| 12/4/21 | Fredonia, NY (Dods Hall) | Cortland 71, Fredonia 55 | Box score |
| 12/3/21 | Cortland, NY (Corey Gym) | Brockport 87, Cortland 60 | Box score |
| 11/30/21 | Oswego, NY (Max Ziel Gym) | Oswego 69, Cortland 44 | Box score |
| 11/20/21 | Elmira, NY (Speidel Gym) | Cortland 83, Elmira 63 | Box score |
| 11/17/21 | Ithaca, NY (Ben Light Gymnasium) | Ithaca 72, Cortland 63 | Box score |
| 11/13/21 | Rochester, NY | Cortland 92, Houghton 64 | Box score |
| 11/12/21 | Rochester, NY (Palestra) | Rochester (NY) 79, Cortland 53 | Box score |